Recombinant Rat Polymeric immunoglobulin receptor(Pigr)

Code CSB-CF017981RA
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P15083
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Rattus norvegicus (Rat)
Sequence QSPIFGPQDVSSIEGNSVSITCYYPDTSVNRHTRKYWCRQGANGYCATLISSNGYLSKEYSGRASLINFPENSTFVINIAHLTQEDTGSYKCGLGTTNRGLFFDVSLEVSQVPEFPNDTHVYTKDIGRTVTIECRFKEGNAHSKKSLCKKRGEACEVVIDSTEYVDPSYKDRAILFMKGTSRDIFYVNISHLIPSDAGLYVCQAGEGPSADKNNADLQVLEPEPELLYKDLRSSVTFECDLGREVANDAKYLCRKNKETCDVIINTLGKRDPAFEGRILLTPRDDNGRFSVLITGLRKEDAGHYQCGAHSSGLPQEGWPVQAWQLFVNEESTIPNSRSVVKGVTGGSVAIVCPYNPKESSSLKYWCHWEADENGRCPVLVGTQALVQEGYEGRLALFDQPGSGAYTVILNQLTTQDSGFYWCLTDGDSRWRTTIELQVAEATKKPDLEVTPQNATAVIGETFTISCHYPCKFYSQEKYWCKWSNDGCHILPSHDEGARQSSVSCDQSSQIVSMTLNPVKKEDEGWYWCGVKEGQVYGETTAIYVAVEERTRGSPHINPTDANARAKDAPEEEAMESSVREDENKANLDPRLFADEREIQNAGDQAQENRASGNAGSAGGQSGSSKVLFSTLVPLGLVLAVGAVAVWVARVRHRKNVDRMSISSYRTDISMGDFRNSRDLGGNDNMGATPDTQETVLEGKDEIETTTECTTEPEESKKAKRSSKEEADMAYSAFLFQSSTIAAQVHDGPQEA
Source in vitro E.coli expression system
Gene Names Pigr
Protein Names Recommended name: Polymeric immunoglobulin receptor Short name= PIgR Short name= Poly-Ig receptor Cleaved into the following chain: 1. Secretory component
Expression Region 19-769
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Subcellular Location Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Secretory component: Secreted
Database Links

KEGG: rno:25046

STRING: 10116.ENSRNOP00000005853

UniGene: Rn.234069

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