Recombinant Rat Probable G-protein coupled receptor 88 (Gpr88)

Code CSB-CF872148RA
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Source in vitro E.coli expression system
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Product Details

Target Names
Uniprot No.
Alternative Names
Gpr88; Strg; Probable G-protein coupled receptor 88; Striatum-specific G-protein coupled receptor
Rattus norvegicus (Rat)
Expression Region
Target Protein Sequence
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Please contact us to get it.

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Target Background

Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function.
Gene References into Functions
  1. Therefore, we conclude that GPR88 and GPR124 receptors may be involved in the development or maintenance of high blood pressure. PMID: 28678544
  2. In the developing cortex, GPR88 shifts on the day of birth to the nuclei of neurons in layers V to II. PMID: 26918661
  3. Results suggest a role for Gpr88 in the regulation of cognitive and motor functions, and support its relevance to the pathophysiology and treatment of schizophrenia and other disorders involving dysfunction of the accumbens-striatal complex PMID: 25155879
  4. GPR88 is confined to striatal medium spiny neurons and indicate that L-DOPA-mediated behavioural effects in hemiparkinsonian rats may involve normalization of striatal GPR88 levels PMID: 19656174
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Expressed predominantly in the striatum. Expressed also in olfactory tubercle, nucleus accumbens, amygdala, and neocortex. Spinal cord, pons, and medulla expression remains discrete. Also expressed in peripheral tissues, including adrenal cortex (E16-E21)
Database Links
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