Recombinant Saccharomyces cerevisiae Peroxisomal biogenesis factor 3(PEX3)

Code CSB-CF017804SVG
Size Pls inquire other sizes
Source in vitro E.coli expression system
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Product Details

Target Names PEX3
Uniprot No. P28795
Alternative Names PEX3; PAS3; YDR329C; D9798.15; Peroxisomal biogenesis factor 3; Peroxin-3; Peroxisomal membrane protein PAS3
Species Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Expression Region 1-441
Protein Length full length protein
Tag Info The following tags are available.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

Target Data

Function Involved in peroxisome biosynthesis. May function as a receptor protein. Lack of this protein causes the peroxisomal-deficient phenotype and mislocalization in the cytosol of peroxisomal matrix proteins.
Gene References into Functions
  1. Using a combination of microscopy and biochemical approaches, we show that a subset of the PMPs, including the receptor docking protein Pex14, localizes to membrane vesicles in S. cerevisiae pex3 cells. PMID: 28552664
  2. a shift to shorter (C18-->C16) acyl chains contributes to the reduced binding of alphaS to lipid droplets in pex3Delta cells PMID: 23916615
  3. It was concluded that Pex3 recruits the pexophagy receptor Atg36. This reinforces the pivotal role played by Pex3 in coordinating the size of the peroxisome pool, and establishes its role in pexophagy in S. cerevisiae. PMID: 22643220
  4. Data conclude that natural or artificial targeting of Pex3p to any endomembrane may initiate peroxisome formation and that also Pex3p-containing mitochondria can serve as source for the de novo synthesis of peroxisomes. PMID: 20655617
  5. The PEX3 protein could first be observed in the endoplasmic reticulum (ER), where it concentrates in foci that then bud off in a Pex19-dependent manner and mature into fully functional peroxisomes. PMID: 16009135
  6. Pex3p functions as an anchor for inheritance protein Inp1p at the peroxisomal membrane, independently of its role at the endoplasmic reticulum in peroxisome biogenesis. PMID: 19948495

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Subcellular Location Peroxisome membrane, Single-pass membrane protein
Protein Families Peroxin-3 family
Database Links

KEGG: sce:YDR329C

STRING: 4932.YDR329C


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