Recombinant Two pore potassium channel protein sup-9(sup-9)

Code CSB-CF521172CXY
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names sup-9
Uniprot No. O17185
Alternative Names sup-9; F34D6.3; Two pore potassium channel protein sup-9; Suppressor of unc-93 protein 9; n2P38
Species Caenorhabditis elegans
Expression Region 1-329
Target Protein Sequence MKRQNIRTLSLIVCTLTYLLVGAAVFDALETENEILQRKLVQRVREKLKTKYNMSNADYE ILEATIVKSVPHKAGYQWKFSGAFYFATTVITTIGYGHSTPMTDAGKVFCMLYALAGIPL GLIMFQSIGERMNTFAAKLLRFIRRAAGKQPIVTSSDLIIFCTGWGGLLIFGGAFMFSSY ENWTYFDAVYYCFVTLTTIGFGDYVALQKRGSLQTQPEYVFFSLVFILFGLTVISAAMNL LVLRFLTMNTEDERRDEQEAILAAQGLVRVGDPTADDDFGRLPLSDNVSLASCSCYQLPD EKLRHRHRKHTEPHGGPPTFSGMTTRPKY
Protein Length full length protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

Function
Potassium channel involved in coordination of muscle contraction. Activity is regulated by sup-18.
Gene References into Functions
  1. we suggest that the SUP-18 IYD regulates the activity of the SUP-9 channel using NADH as a coenzyme and thus couples the metabolic state of muscle cells to muscle membrane excitability. PMID: 24586202
Subcellular Location Membrane; Multi-pass membrane protein.
Protein Families Two pore domain potassium channel (TC 1.A.1.8) family
Tissue Specificity Low levels along surface of body-wall muscle cells, in vulval and intestinal muscles and, more weakly, in anal depressor and sphincter muscles. Also expressed in a subset of head neurons.
Database Links

KEGG: cel:CELE_F34D6.3

STRING: 6239.F34D6.3

UniGene: Cel.14253

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