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ALPG (WO 2022197890A1 Biosimilar) Recombinant Monoclonal Antibody

Datasheet
Code CSB-RA001633MB1HU
Size
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Product Details

Uniprot No.
P10696
Target Names
ALPG
Alternative Names
Alkaline phosphatase, placental-like；EC 3.1.3.1；ALP-1；Alkaline phosphatase Nagao isozyme；Germ cell alkaline phosphatase；GCAP；Placental alkaline phosphatase-like；PLAP-like, ALPPL2, ALPPL
Species Reactivity
Human
Immunogen
Recombinant Human ALPG protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.40
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Notes
Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.
Lead Time
In stock
Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

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ALPG Antibodies

ALPG Proteins

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Target Background

Function
Alkaline phosphatase that can hydrolyze various phosphate compounds.
Gene References into Functions
  1. aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID: 23467613
  2. These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID: 16412386
  3. Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID: 17009260
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Families
Alkaline phosphatase family
Tissue Specificity
Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.
Database Links

HGNC: 441

OMIM: 171810

KEGG: hsa:251

STRING: 9606.ENSP00000295453

UniGene: Hs.333509

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