ALPG Recombinant Monoclonal Antibody

Datasheet

Code	CSB-RA001633MA1HU
Size	US$210
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Image	The Binding Activity of Human ALPG with Anti-ALPG Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPG (CSB-MP001633HU) at 2 μg/mL can bind Anti-ALPG recombinant antibody , the EC₅₀ is 14.09-23.17 ng/mL. The Binding Activity of Human ALPP with Anti-ALPP/ALPG Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPP (CSB-MP001632HU) at 2 μg/mL can bind Anti-ALPP/ALPG recombinant antibody. The EC₅₀ is 4.478-5.236 ng/mL.
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Target Background

Product Details

Uniprot No.

P10696

Target Names

ALPG

Alternative Names

Alkaline phosphatase, placental-like (EC 3.1.3.1) (ALP-1) (Alkaline phosphatase Nagao isozyme) (Germ cell alkaline phosphatase) (GCAP) (Placental alkaline phosphatase-like) (PLAP-like), ALPPL2, ALPPL

Species Reactivity

Human

Immunogen

Recombinant Human ALPG protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

hIgG1

Clone No.

29A5

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The ALPG recombinant monoclonal antibody was generated through the insertion of ALPG antibody genes into plasmid vectors, followed by transfection into appropriate host cells for exogenous protein expression. Subsequently, this recombinant monoclonal antibody underwent purification using affinity chromatography and validation for ELISA. In functional ELISA assays, it was observed that the ALPG recombinant monoclonal antibody could effectively bind to the human ALPG protein (CSB-MP001633HU) at a concentration of 2 μg/mL, demonstrating an EC₅₀ range of 14.09-23.17 ng/mL.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Alkaline phosphatase that can hydrolyze various phosphate compounds.

Gene References into Functions

aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID: 23467613
These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID: 16412386
Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID: 17009260

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Families

Alkaline phosphatase family

Tissue Specificity

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

Database Links

HGNC: 441

OMIM: 171810

KEGG: hsa:251

STRING: 9606.ENSP00000295453

UniGene: Hs.333509

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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CEACAM5: A Promising Member of CEACAM Family, A Potential Target for ADC Drug Research! ALPG: a Germ Cell-Associated Alkaline Phosphatase (ALP), a Highly Specific Cell Surface Antigen in Cancers! Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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