ALPG Recombinant Monoclonal Antibody

Code CSB-RA001633MA1HU
Size US$210
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  • The Binding Activity of Human ALPG with Anti-ALPG Recombinant Antibody
    Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPG (CSB-MP001633HU) at 2 μg/mL can bind Anti-ALPG recombinant antibody , the EC50 is 14.09-23.17 ng/mL.
  • The purity of ALPG was greater than 95% as determined by SEC-HPLC
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Product Details

Uniprot No.
Target Names
ALPG
Alternative Names
Alkaline phosphatase, placental-like (EC 3.1.3.1) (ALP-1) (Alkaline phosphatase Nagao isozyme) (Germ cell alkaline phosphatase) (GCAP) (Placental alkaline phosphatase-like) (PLAP-like), ALPPL2, ALPPL
Species Reactivity
Human
Immunogen
Recombinant Human ALPG protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Isotype
hIgG1
Clone No.
29A5
Purification Method
Affinity-chromatography
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The ALPG recombinant monoclonal antibody was generated through the insertion of ALPG antibody genes into plasmid vectors, followed by transfection into appropriate host cells for exogenous protein expression. Subsequently, this recombinant monoclonal antibody underwent purification using affinity chromatography and validation for ELISA. In functional ELISA assays, it was observed that the ALPG recombinant monoclonal antibody could effectively bind to the human ALPG protein (CSB-MP001633HU) at a concentration of 2 μg/mL, demonstrating an EC50 range of 14.09-23.17 ng/mL.

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Target Background

Function
Alkaline phosphatase that can hydrolyze various phosphate compounds.
Gene References into Functions
  1. aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID: 23467613
  2. These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID: 16412386
  3. Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID: 17009260
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Families
Alkaline phosphatase family
Tissue Specificity
Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.
Database Links

HGNC: 441

OMIM: 171810

KEGG: hsa:251

STRING: 9606.ENSP00000295453

UniGene: Hs.333509

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