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DPEP3 (US10189910B2 Biosimilar) Recombinant Monoclonal Antibody

DPEP3 (US10189910B2 Biosimilar) Recombinant Monoclonal Antibody

Datasheet

Code	CSB-RA007125MB1HU
Size	US$9799
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Product Details
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Target Background

Product Details

Uniprot No.

Q9H4B8

Target Names

DPEP3

Alternative Names

Dipeptidase 3 antibody; DPEP3 antibody; UNQ834/PRO1772 antibody

Species Reactivity

Human

Immunogen

Recombinant Human DPEP3 protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

0.01M PBS，pH7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Notes

Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.

Lead Time

In stock

Description

This recombinant monoclonal antibody is developed as a research-grade biosimilar to the reference antibody described in patent US10189910B2, specifically targeting DPEP3 (Dipeptidase 3). DPEP3 is a membrane-bound metallopeptidase that catalyzes the hydrolysis of dipeptides and plays a role in cellular metabolism and peptide processing. This enzyme belongs to the dipeptidase family and is expressed in various tissues, where it participates in the final steps of protein degradation and amino acid recycling. DPEP3 has been implicated in metabolic processes and may have relevance in studies of cellular homeostasis and nutrient sensing pathways.

The reference antibody outlined in US10189910B2 provides a well-characterized framework for investigating DPEP3 expression and function in biological systems. This biosimilar antibody serves as a valuable research tool for scientists studying dipeptidase biology, metabolic regulation, and related cellular mechanisms. It enables researchers to explore DPEP3's role in various physiological and pathological contexts, supporting investigations into enzyme function and potential disease associations.

Usage

It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

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Target Background

Function

Dipeptidase that hydrolyzes cystinyl-bis-glycine. Does not hydrolyze leukotriene D4 (LTD4) into leukotriene E4 (LTE4).

Gene References into Functions

This paper describes differences in substrate specificity and tissue distribution of membrane-bound dipeptidase 3 from mouse in comparison to other mouse members of this family. PMID: 12738806

Subcellular Location

Membrane; Lipid-anchor, GPI-anchor.

Protein Families

Metallo-dependent hydrolases superfamily, Peptidase M19 family

Database Links

HGNC: 23029

OMIM: 609926

KEGG: hsa:64180

STRING: 9606.ENSP00000268793

UniGene: Hs.302028

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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