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KAAG1 (CN 103492418 A Biosimilar) Recombinant Monoclonal Antibody

Datasheet
Code CSB-RA871385MB1HU
Size US$9799
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Product Details

Uniprot No.
Q9UBP8
Target Names
KAAG1
Alternative Names
Kidney-associated antigen 1, RU2 antisense gene protein, KAAG1, RU2AS
Species Reactivity
Human
Immunogen
Recombinant Human KAAG1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
0.01M PBS，pH7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Notes
Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.
Lead Time
In stock
Description

This recombinant monoclonal antibody is a research-grade biosimilar of the anti-KAAG1 antibody described in CN 103492418 A, targeting KAAG1 (Kidney-Associated Antigen 1), a tumor-associated antigen reported to be present on the surface of certain cancer cells with restricted expression in normal tissues. KAAG1 has been described as being expressed across multiple malignancies—such as ovarian cancer, triple-negative breast cancer, and castration-resistant prostate cancer—making it a useful marker/target for studying tumor antigen biology and target expression heterogeneity in oncology models.

CN 103492418 A discloses KAAG1-binding antibodies and antigen-binding fragments proposed for cancer detection/diagnosis and therapeutic delivery concepts (e.g., using the antibody to deliver a therapeutic moiety to KAAG1-expressing cells). This biosimilar provides the antibody component alone, enabling researchers to investigate KAAG1 antigen profiling, antibody binding specificity, and cell-surface target engagement/internalization behavior in controlled systems—supporting early-stage evaluation of KAAG1 as an oncology target and informing design considerations for payload-based modalities (e.g., ADC concepts) without confounding payload cytotoxicity.

Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

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