MYL9 (US10513561B2 Biosimilar) Recombinant Monoclonal Antibody

1. MYL9 expression might be a promising prognostic marker and therapeutic target in ESCC PMID: 28388691
2. At the cleavage furrow Arv1 recruits myosin heavy chain 9 (MYH9) and myosin light chain 9 (MYL9) by interacting with IQ-motif-containing GTPase-activating protein (IQGAP1). PMID: 27104745
3. These findings suggested that low MYLK and MYL9 expressions might be associated with the development of NSCLC. PMID: 25179839
4. the decreased expression of MYL9 may play an important role in tumor progression of prostate cancer PMID: 24338276
5. Overexpression of MRTF-A significantly promoted the migration of MCF-7 cells through its transactivation effects on MYL9 and CYR61 genes PMID: 24084383
6. Overexpression of SMYD3 promotes MRTF-A-mediated upregulation of MYL9 and migration of MCF-7 breast cancer cells PMID: 24189459
7. surface CD3 expression proceeds through both MYL9-dependent and MYL9-independent pathways (i.e. the protein kinase C- dependent pathway) in Jurkat cells. PMID: 23538510
8. The FHC-mediated structural perturbations in RLC that affect Ca(2+) binding properties of mutated myocardium are responsible for triggering the abnormal function of the heart that in turn might initiate a hypertrophic process and lead to heart failure. PMID: 16076902
9. Smooth muscle type isoform, MLC-2C, is the inducible isoform, and might play a crucial role in monocyte/macrophage cell lineage. PMID: 18480596
10. use of a shRNA to decrease MYL9 expression showed that MYL9 was involved in proplatelet formation PMID: 19724058

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HGNC: 15754

OMIM: 609905

KEGG: hsa:10398

STRING: 9606.ENSP00000279022

UniGene: Hs.504687