A4GNT Antibody

Code CSB-PA797885
Size US$297
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  • Western blot analysis of extracts from K562 cells, using A4GNT antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) A4GNT Polyclonal antibody
Uniprot No.
Target Names
A4GNT
Alternative Names
4-N-acetylglucosaminyltransferase antibody; A4GCT_HUMAN antibody; A4GNT antibody; Alpha 1 4 N acetylglucosaminyltransferase antibody; Alpha-1 antibody; Alpha4GnT antibody; EC 2.4.1. antibody; MGC149493 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human A4GNT.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas.
Gene References into Functions
  1. human alpha1,4-N-acetylglucosaminyltransferase (alpha4GnT) is responsible for O-glycan biosynthesis and has a role in preventing gastric cancer by inhibiting H. pylori infection and also suppressing tumor-promoting inflammation PMID: 22307328
  2. Up-regulation of alpha-1,4-N-acetylglucosaminyltransferase is associated with pancreatic cancer PMID: 16441422
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 32 family
Tissue Specificity
Detected in stomach and pancreas.
Database Links

HGNC: 17968

KEGG: hsa:51146

STRING: 9606.ENSP00000236709

UniGene: Hs.278960

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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