ACAD8 Antibody

Code CSB-PA892457LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse liver tissue, Mouse heart tissue, Mouse skeletal muscle tissue
    All lanes: ACAD8 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 46, 32, 39 kDa
    Observed band size: 46, 39 kDa

  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA892457LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACAD8 Polyclonal antibody
Uniprot No.
Target Names
ACAD8
Alternative Names
ACAD 8 antibody; ACAD-8 antibody; ACAD8 antibody; ACAD8_HUMAN antibody; Activator-recruited cofactor 42 kDa component antibody; Acyl CoA dehydrogenase family member 8 antibody; Acyl Coenzyme A dehydrogenase family member 8 antibody; Acyl-CoA dehydrogenase family member 8 antibody; ARC42 antibody; FLJ22590 antibody; IBD antibody; Isobutyryl-CoA dehydrogenase antibody; Isobutyryl-CoA dehydrogenase; mitochondrial antibody; mitochondrial antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Isobutyryl-CoA dehydrogenase, mitochondrial protein (201-415AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ACAD8 Antibody (Product code: CSB-PA892457LA01HU) is Non-conjugated. For ACAD8 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA892457LB01HU ACAD8 Antibody, HRP conjugated ELISA
FITC CSB-PA892457LC01HU ACAD8 Antibody, FITC conjugated
Biotin CSB-PA892457LD01HU ACAD8 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Isobutyryl-CoA dehydrogenase which catalyzes one of the steps of the valine catabolic pathway. To a lesser extent, is also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA.
Gene References into Functions
  1. we discovered a novel c.1156_1158delCAG mutation in ACAD8 in patients with isobutyryl-CoA dehydrogenase deficiency , and investigated the mutation spectrum of ACAD8. PMID: 24635911
  2. first enzymatic and molecular confirmation of a deficiency of this enzyme in a patient PMID: 12359132
Involvement in disease
Isobutyryl-CoA dehydrogenase deficiency (IBDD)
Subcellular Location
Mitochondrion.
Protein Families
Acyl-CoA dehydrogenase family
Tissue Specificity
Detected at comparable levels in all tissues examined (heart, lung, brain, skeletal muscle, pancreas and placenta). Weakly expressed in liver and kidney.
Database Links

HGNC: 87

OMIM: 604773

KEGG: hsa:27034

STRING: 9606.ENSP00000281182

UniGene: Hs.14791

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