ACBD5 Antibody

Code CSB-PA725893HA01HU
Size US$166
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Image
  • Western blot
    All lanes: ACBD5 antibody at 2µg/ml + Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 61, 55, 59, 47 kDa
    Observed band size: 61 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACBD5 Polyclonal antibody
Uniprot No.
Target Names
ACBD5
Alternative Names
Acbd5 antibody; ACBD5_HUMAN antibody; Acyl CoA binding domain containing 5 antibody; Acyl CoA binding domain containing protein 5 antibody; Acyl Coenzyme A binding domain containing 5 antibody; Acyl-CoA-binding domain-containing protein 5 antibody; DKFZp434A2417 antibody; Endozepine related protein antibody; KIAA1996 antibody; Membrane associated diazepam binding inhibitor antibody; OTTHUMP00000019362 antibody; OTTHUMP00000019363 antibody; OTTHUMP00000019364 antibody; OTTHUMP00000019365 antibody; RP11-85G18.5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Acyl-CoA-binding domain-containing protein 5 protein (1-461AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ACBD5 Antibody (Product code: CSB-PA725893HA01HU) is Non-conjugated. For ACBD5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA725893HB01HU ACBD5 Antibody, HRP conjugated ELISA
FITC CSB-PA725893HC01HU ACBD5 Antibody, FITC conjugated
Biotin CSB-PA725893HD01HU ACBD5 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
Gene References into Functions
  1. ACBD5 captures VLC-CoAs on the cytosolic side of the peroxisomal membrane so that the transport of VLC-CoAs into peroxisomes and subsequent beta-oxidation thereof can proceed efficiently. PMID: 27899449
  2. ACBD5-VAPB interaction regulates peroxisome-endoplasmic reticulum associations. Loss of PO-ER association perturbs PO membrane expansion and increases PO movement. PMID: 28108524
  3. VAP-ACBD5-mediated contact between the endoplasmic reticulum and peroxisomes mediate organelle maintenance and lipid homeostasis. PMID: 28108526
  4. Findings suggest that the ACBD5-RET rearrangement is causatively involved in the development of papillary thyroid cancer. PMID: 25175022
  5. Yeast Atg37, which is homologous to human ACBD5, is involved in autophagy of peroxisomes. PMID: 24905344
  6. A mutation in the acyl-coenzyme A binding domain-containing protein 5 gene (ACBD5 ) may have a role in autosomal dominant thrombocytopenia PMID: 20626622

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Subcellular Location
Peroxisome membrane; Single-pass membrane protein.
Protein Families
ATG37 family
Database Links

HGNC: 23338

OMIM: 616618

KEGG: hsa:91452

STRING: 9606.ENSP00000379568

UniGene: Hs.530597

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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