ACOT12 Antibody

Datasheet

Code	CSB-PA066461
Size	US$297
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Image	Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using ACOT12 antibody. Immunofluorescence analysis of A549 cells, using ACOT12 antibody.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ACOT12 Polyclonal antibody

Uniprot No.

Q8WYK0

Target Names

ACOT12

Alternative Names

ACO12_HUMAN antibody; Acot12 antibody; Acyl CoA thioester hydrolase 12 antibody; Acyl CoA thioesterase 12 antibody; Acyl-CoA thioester hydrolase 12 antibody; Acyl-CoA thioesterase 12 antibody; Acyl-coenzyme A thioesterase 12 antibody; Cach antibody; CACH-1 antibody; CACH1 antibody; Cytoplasmic acetyl CoA hydrolase 1 antibody; Cytoplasmic acetyl-CoA hydrolase 1 antibody; cytosolic acetyl CoA hydrolase antibody; hCACH-1 antibody; hCACH1 antibody; MGC105114 antibody; StAR related lipid transfer (START) domain containing 15 antibody; StARD15 antibody; START domain containing protein 12 antibody; START domain-containing protein 15 antibody; THEAL antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human ACOT12.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,IHC,IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:50-1:100
IF	1:100-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes acetyl-CoA.

Gene References into Functions

using a range of structural and biophysical techniques, it is demonstrated that ACOT12 is a trimer rather than a tetramer and that neither ADP nor ATP exert their regulatory effects by altering the oligomeric status of the enzyme PMID: 25002576
The human CACH cDNA encodes a 555-amino-acid sequence that is 81.4%/78.7% identical to those of the mouse/rat homologue, suggesting a conserved role for this enzyme in the human and rodent livers. PMID: 16951743

Subcellular Location

Cytoplasm, cytosol.

Database Links

HGNC: 24436

OMIM: 614315

KEGG: hsa:134526

STRING: 9606.ENSP00000303246

UniGene: Hs.591756

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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