ACOT12 Antibody

Code CSB-PA007167
Size US$119
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Product Details

Uniprot No.
Target Names
ACOT12
Alternative Names
ACO12_HUMAN antibody; Acot12 antibody; Acyl CoA thioester hydrolase 12 antibody; Acyl CoA thioesterase 12 antibody; Acyl-CoA thioester hydrolase 12 antibody; Acyl-CoA thioesterase 12 antibody; Acyl-coenzyme A thioesterase 12 antibody; Cach antibody; CACH-1 antibody; CACH1 antibody; Cytoplasmic acetyl CoA hydrolase 1 antibody; Cytoplasmic acetyl-CoA hydrolase 1 antibody; cytosolic acetyl CoA hydrolase antibody; hCACH-1 antibody; hCACH1 antibody; MGC105114 antibody; StAR related lipid transfer (START) domain containing 15 antibody; StARD15 antibody; START domain containing protein 12 antibody; START domain-containing protein 15 antibody; THEAL antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human ACOT12.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes acetyl-CoA.
Gene References into Functions
  1. using a range of structural and biophysical techniques, it is demonstrated that ACOT12 is a trimer rather than a tetramer and that neither ADP nor ATP exert their regulatory effects by altering the oligomeric status of the enzyme PMID: 25002576
  2. The human CACH cDNA encodes a 555-amino-acid sequence that is 81.4%/78.7% identical to those of the mouse/rat homologue, suggesting a conserved role for this enzyme in the human and rodent livers. PMID: 16951743
Subcellular Location
Cytoplasm, cytosol.
Database Links

HGNC: 24436

OMIM: 614315

KEGG: hsa:134526

STRING: 9606.ENSP00000303246

UniGene: Hs.591756

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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