ACOT12 Antibody

Code CSB-PA066461
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using ACOT12 antibody.
  • Immunofluorescence analysis of A549 cells, using ACOT12 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACOT12 Polyclonal antibody
Uniprot No.
Target Names
ACOT12
Alternative Names
ACO12_HUMAN antibody; Acot12 antibody; Acyl CoA thioester hydrolase 12 antibody; Acyl CoA thioesterase 12 antibody; Acyl-CoA thioester hydrolase 12 antibody; Acyl-CoA thioesterase 12 antibody; Acyl-coenzyme A thioesterase 12 antibody; Cach antibody; CACH-1 antibody; CACH1 antibody; Cytoplasmic acetyl CoA hydrolase 1 antibody; Cytoplasmic acetyl-CoA hydrolase 1 antibody; cytosolic acetyl CoA hydrolase antibody; hCACH-1 antibody; hCACH1 antibody; MGC105114 antibody; StAR related lipid transfer (START) domain containing 15 antibody; StARD15 antibody; START domain containing protein 12 antibody; START domain-containing protein 15 antibody; THEAL antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human ACOT12.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC,IF
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes acetyl-CoA.
Gene References into Functions
  1. using a range of structural and biophysical techniques, it is demonstrated that ACOT12 is a trimer rather than a tetramer and that neither ADP nor ATP exert their regulatory effects by altering the oligomeric status of the enzyme PMID: 25002576
  2. The human CACH cDNA encodes a 555-amino-acid sequence that is 81.4%/78.7% identical to those of the mouse/rat homologue, suggesting a conserved role for this enzyme in the human and rodent livers. PMID: 16951743
Subcellular Location
Cytoplasm, cytosol.
Database Links

HGNC: 24436

OMIM: 614315

KEGG: hsa:134526

STRING: 9606.ENSP00000303246

UniGene: Hs.591756

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