ACOT13 Antibody

1. Markers in DYX2 genes KIAA0319 and FAM65B were associated with cortical thickness in the left developing orbitofrontal region and global fractional anisotropy, respectively. KIAA0319 and ACOT13 were suggestively associated with overall fractional anisotropy and left pars opercularis cortical thickness, respectively. PMID: 25953057
2. This study models the reaction of the hTHEM2 enzyme by first-principles methods to elucidate atomic and electronic details of the mechanism, its transition-state (TS) conformation, and the free-energy landscape of the process. PMID: 24894958
3. study failed to show any association of THEM2 SNPs with developmental dyslexia in an Indian population. PMID: 23954868
4. The results of this study confirmed that both FOXP2 and KIAA0319/TTRAP/THEM2 genes play an important role in human language development, but probably through different cerebral pathways. PMID: 22262880
5. analysis of human thioesterase superfamily member 2 crystal structure PMID: 16934754
6. Small interference RNA silencing in cell line HCT116 shows that the hthem2 gene is essential for the cell sustained proliferation. PMID: 17045243
7. Yeast two-hybrid screening using libraries prepared from mouse liver and embryo identified Them2 (thioesterase superfamily member 2) and the homeodomain transcription factor Pax3 (paired box gene 3), respectively, as PC-TP-interacting proteins. PMID: 17704541
8. The physiological role of hTHEM2 involves catalysis of the hydrolysis of cytosolic medium-to-long-chain acyl-CoA thioesters. PMID: 19170545

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HGNC: 20999

OMIM: 615652

KEGG: hsa:55856

STRING: 9606.ENSP00000230048

UniGene: Hs.731605