ACOT4 Antibody

Datasheet

Code	CSB-PA051355
Size	US$297
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Image	Western blot analysis of extracts from HeLa cells and COLO cells, using ACOT4 antibody. Immunofluorescence analysis of MCF-7 cells, using ACOT4 antibody.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ACOT4 Polyclonal antibody

Uniprot No.

Q8N9L9

Target Names

ACOT4

Alternative Names

ACOT4 antibody; ACOT4_HUMAN antibody; Acyl-CoA thioesterase 4 antibody; Acyl-coenzyme A thioesterase 4 antibody; Peroxisomal acyl CoA thioesterase 2B antibody; Peroxisomal acyl coenzyme A thioester hydrolase Ib antibody; Peroxisomal long-chain acyl-CoA thioesterase Ib antibody; PTE-2b antibody; PTE-Ib antibody; Pte1b antibody; Pte2b antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of Human ACOT4.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB,IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000
IF	1:100-1:500

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Functions as a peroxisomal succinyl-coenzyme A thioesterase that can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs.

Gene References into Functions

Exome sequencing revealed an association with ACOT4 and increased risk of ischemic stroke. PMID: 25961151
ACOT4 and ACOT8 are responsible for the termination of beta-oxidation of dicarboxylic acids of medium-chain length with the concomitant release of the corresponding free acids PMID: 16141203

Subcellular Location

Peroxisome.

Protein Families

C/M/P thioester hydrolase family

Tissue Specificity

Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.

Database Links

HGNC: 19748

OMIM: 614314

KEGG: hsa:122970

STRING: 9606.ENSP00000323071

UniGene: Hs.49433

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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