ACOT4 Antibody

Code CSB-PA000804
Size US$100
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  • Western Blot analysis of COLO205 cells using ACOT4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ACOT4
Alternative Names
ACOT4 antibody; ACOT4_HUMAN antibody; Acyl-CoA thioesterase 4 antibody; Acyl-coenzyme A thioesterase 4 antibody; Peroxisomal acyl CoA thioesterase 2B antibody; Peroxisomal acyl coenzyme A thioester hydrolase Ib antibody; Peroxisomal long-chain acyl-CoA thioesterase Ib antibody; PTE-2b antibody; PTE-Ib antibody; Pte1b antibody; Pte2b antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human ACOT4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Functions as a peroxisomal succinyl-coenzyme A thioesterase that can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs.
Gene References into Functions
  1. Exome sequencing revealed an association with ACOT4 and increased risk of ischemic stroke. PMID: 25961151
  2. ACOT4 and ACOT8 are responsible for the termination of beta-oxidation of dicarboxylic acids of medium-chain length with the concomitant release of the corresponding free acids PMID: 16141203
Subcellular Location
Peroxisome.
Protein Families
C/M/P thioester hydrolase family
Tissue Specificity
Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.
Database Links

HGNC: 19748

OMIM: 614314

KEGG: hsa:122970

STRING: 9606.ENSP00000323071

UniGene: Hs.49433

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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