AGTPBP1 Antibody

Code CSB-PA001464GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
AGTPBP1
Alternative Names
CCP1 antibody; 1700020N17Rik antibody; 2310001G17Rik antibody; 2900054O13Rik antibody; 4930445M19Rik antibody; 5730402G09Rik antibody; AGTPBP 1 antibody; AGTPBP1 antibody; ATP/GTP binding protein 1 antibody; ATP/GTP-binding protein 1 antibody; BB114605 antibody; Carboxypeptidase tubulin antibody; CBPC1_HUMAN antibody; Cytosolic carboxypeptidase 1 antibody; DKFZp686M20191 antibody; KIAA1035 antibody; MGC90651 antibody; mKIAA1035 antibody; Nervous system nuclear protein induced by axotomy antibody; Nervous system nuclear protein induced by axotomy protein 1 homolog antibody; nmf243 antibody; NNA1 antibody; OTTHUMP00000021581 antibody; OTTHUMP00000063553 antibody; pcd antibody; Purkinje cell degeneration antibody; RP11-30C23.1 antibody; Soluble carboxypeptidase antibody; Tubulinyl Tyr carboxypeptidase antibody; Tyrosine carboxypeptidase antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human AGTPBP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis.
Gene References into Functions
  1. we identified seven new putative CCP1 substrates, all of them harboring acidic amino acids in their gene-encoded C terminus PMID: 25381060
  2. Data indicate that a functional nuclear export signals (NESs) in CCP1 that mediates direct binding to the export receptor CRM1. PMID: 23242554
Subcellular Location
Cytoplasm. Cytoplasm, cytosol. Nucleus. Mitochondrion.
Protein Families
Peptidase M14 family
Database Links

HGNC: 17258

OMIM: 606830

KEGG: hsa:23287

STRING: 9606.ENSP00000365251

UniGene: Hs.719980

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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