ALG1 Antibody

Code CSB-PA001593GA01HU
Size $600
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Target Names
ALG1
Alternative Names
4-mannosyltransferase antibody; Alg1 antibody; ALG1_HUMAN antibody; asparagine-linked glycosylation 1 homolog (yeast; beta-1,4-mannosyltransferase) antibody; asparagine-linked glycosylation 1; beta-1,4-mannosyltransferase homolog (S. cerevisiae) antibody; Asparagine-linked glycosylation protein 1 homolog antibody; Beta 1 4 mannosyltransferase antibody; Beta-1 antibody; CDG1K antibody; Chitobiosyldiphosphodolichol beta-mannosyltransferase antibody; GDP Man GlcNAc2 PP dolichol mannosyltransferase antibody; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase antibody; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase antibody; Hmat-1 antibody; HMAT1 antibody; HMT 1 antibody; HMT1 antibody; Mannosyltransferase 1 antibody; Mannosyltransferase-1 antibody; MT 1 antibody; MT-1 antibody; MT1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ALG1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
Gene References into Functions
  1. evaluated the genetic association of WDR3 and ALG1 in schizophrenia. We examined 21 single nucleotide polymorphisms [SNPs; W1 (rs1812607)-W16 (rs6656360), A1 (rs8053916)-A10 (rs9673733)] from these genes using the Japanese case-control sample (1,808 schizophrenics and 2,170 matched controls). No significant genetic associations of these SNPs were identified. However, we detected a significant association of W4 (rs319471) PMID: 29309433
  2. Study presents molecular, clinical and biochemical findings in the largest collection of ALG1-CDG cases ever reported at a single time with 39 cases, bringing the total number to 57. This ranks it the third most common CDG type behind PMM2-CDG and ALG6-CDG. In addition, highly lethal genotype were identified and confirm the presence of a unique xeno-tetrasaccharide in ALG1-CDG patients. PMID: 26931382
  3. In title. PMID: 25649379
  4. Was detected in the patient's ALG1-coding sequence. PMID: 24157261
  5. Family study defining the phenotype of deficiency of beta-1,4 mannosyltransferase (MT-1) congenital disorder of glycosylation (CDG), due to ALG1 gene mutations. Four novel ALG1 mutations were identified. PMID: 22966035
  6. DNA sequencing of ALG1 revealed nine different mutations, seven of which have not been previously reported. Clinical presentations of deficiency are severe, with dysmorphias, CNS involvement and ocular disturbances PMID: 20679665

Show More

Hide All

Involvement in disease
Congenital disorder of glycosylation 1K (CDG1K)
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase group 1 family, Glycosyltransferase 33 subfamily
Database Links

HGNC: 18294

OMIM: 605907

KEGG: hsa:56052

STRING: 9606.ENSP00000262374

UniGene: Hs.592086

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*