ANKRD28 Antibody

Datasheet

Code	CSB-PA929390
Size	US$166
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Image	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: CSB-PA929390(ANKRD28 Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 hours
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Product Details
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Target Background

Product Details

Uniprot No.

O15084

Target Names

ANKRD28

Alternative Names

ANKRD28 antibody; KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody; PP6-ARS-A antibody; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody; Ankyrin repeat domain-containing protein 28 antibody; Phosphatase interactor targeting protein hnRNP K antibody; PITK antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human ANKRD28

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.

Gene References into Functions

findings suggest that BRCA1 is a novel modulator of PP6 signalling via its interaction with ANKRD28. PMID: 27026398
hnRNP K and hnRNP L may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation PMID: 25902538
These findings provide a putative mechanism by which transcriptional activity of hnRNP K can be discretely controlled through the regulation of PP1 activity. PMID: 16564677
CaMKII and GSK3 mediate regulation of PITK. PMID: 17023142
ANKRD28, a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation. PMID: 19118547

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Subcellular Location

Nucleus, nucleoplasm. Note=Seems to be excluded from nucleoli.

Database Links

HGNC: 29024

OMIM: 611122

KEGG: hsa:23243

STRING: 9606.ENSP00000382379

UniGene: Hs.335239

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Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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