ANKRD28 Antibody

Code CSB-PA929390
Size US$166
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  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: CSB-PA929390(ANKRD28 Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 hours
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Product Details

Uniprot No.
Target Names
ANKRD28
Alternative Names
ANKRD28 antibody; KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody; PP6-ARS-A antibody; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody; Ankyrin repeat domain-containing protein 28 antibody; Phosphatase interactor targeting protein hnRNP K antibody; PITK antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human ANKRD28
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation.
Gene References into Functions
  1. findings suggest that BRCA1 is a novel modulator of PP6 signalling via its interaction with ANKRD28. PMID: 27026398
  2. hnRNP K and hnRNP L may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation PMID: 25902538
  3. These findings provide a putative mechanism by which transcriptional activity of hnRNP K can be discretely controlled through the regulation of PP1 activity. PMID: 16564677
  4. CaMKII and GSK3 mediate regulation of PITK. PMID: 17023142
  5. ANKRD28, a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation. PMID: 19118547

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Subcellular Location
Nucleus, nucleoplasm. Note=Seems to be excluded from nucleoli.
Database Links

HGNC: 29024

OMIM: 611122

KEGG: hsa:23243

STRING: 9606.ENSP00000382379

UniGene: Hs.335239

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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