APOBEC2 Antibody

Code CSB-PA001920GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
APOBEC2
Alternative Names
APOBEC2C->U-editing enzyme APOBEC-2 antibody; EC 3.5.4.36 antibody; mRNA(cytosine(6666)) deaminase 2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human APOBEC2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Gene References into Functions
  1. Findings indicate that aberrant APOBEC2 expression causes nucleotide alterations in the transcripts of the specific target gene and could be involved in the development of human hepatocellular carcinoma through hepatic inflammation. PMID: 21469143
  2. Studies indicate the APOBEC family consists of 11 members: APOBEC-1 (Apo1), APOBEC-2 (Apo2), activation induced cytidine deaminase (AID), APOBEC- 3A, -3B, -3C, -3DE, -3F, -3H (Apo3A-H) and APOBEC- 4 (Apo4). PMID: 19911124
  3. The APOBEC2 was confirmed to be elevated in the tonsils with IgAN patients, and the gene expression level was negatively related with serum IgG level in overall patients. PMID: 20138841
  4. crystal structure of APOBEC2 PMID: 17187054
Protein Families
Cytidine and deoxycytidylate deaminase family
Tissue Specificity
Expressed exclusively in heart and skeletal muscle.
Database Links

HGNC: 605

OMIM: 604797

KEGG: hsa:10930

STRING: 9606.ENSP00000244669

UniGene: Hs.555915

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