APOBEC3D/APOBEC3F Antibody

Datasheet

Code	CSB-PA448693
Size	US$297
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Image	Western blot analysis of extracts from MCF-7 cells and COS-7cells, using APOBEC3D/F antibody. Immunohistochemistry analysis of paraffin-embedded human placenta tissue using APOBEC3D/F antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) APOBEC3D/APOBEC3F Polyclonal antibody

Uniprot No.

Q96AK3

Target Names

APOBEC3D/APOBEC3F

Alternative Names

A3D antibody; ABC3D_HUMAN antibody; APOBEC3D antibody; APOBEC3DE antibody; APOBEC3E antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene antibody; ARP6 antibody; bK150C2.9 antibody; BK150C2.9 protein antibody; DNA dC >dU editing enzyme APOBEC 3D antibody; DNA dC->dU-editing enzyme APOBEC-3D antibody; hCG_41704 antibody; HCG41704; isoform CRA_b antibody; Probable DNA dC->dU-editing enzyme APOBEC-3D antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of Human APOBEC3D/F.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000
IHC	1:50-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against Vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.

Subcellular Location

Cytoplasm. Cytoplasm, P-body.

Protein Families

Cytidine and deoxycytidylate deaminase family

Tissue Specificity

Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung.

Database Links

HGNC: 17354

OMIM: 609900

STRING: 9606.ENSP00000216099

UniGene: Hs.629775

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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