APOF Antibody

Code CSB-PA001938GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
APOF
Alternative Names
Apo-F antibody; Apof antibody; APOF_HUMAN antibody; Apolipoprotein F antibody; DKFZp781G18150 antibody; Lipid transfer inhibitor protein antibody; LTIP antibody; MGC22520 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human APOF
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
Gene References into Functions
  1. Direct interactions between C/EBPalpha and ETS-1 were important for high liver-specific expression of ApoF. PMID: 25726912
  2. this study has identified apoF as likely another target gene of FXR. PMID: 24211198
  3. LTIP translocation is dependent on LDL lipid composition PMID: 21937674
  4. LTIP tailors CETP-mediated remodeling of HDL3 and HDL2 particles in subclass-specific ways, strongly implicating it as a regulator of HDL metabolism PMID: 12907677
  5. we have confirmed the negative association between plasma triglyceride levels and Apolipoprotein F previously suggested by a small data set, but now we demonstrate that this effect is seen only in males. PMID: 17901467
  6. lipoprotein composition may influence the status of lipid transfer inhibitor protein activity PMID: 18369235

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Subcellular Location
Secreted.
Protein Families
Apolipoprotein F family
Tissue Specificity
Expressed by the liver and secreted in plasma.
Database Links

HGNC: 615

OMIM: 107760

KEGG: hsa:319

STRING: 9606.ENSP00000381250

UniGene: Hs.534302

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