ARFIP1 Antibody

Code CSB-PA002002GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ARFIP1
Alternative Names
ADP ribosylation factor interacting protein 1 antibody; ADP-ribosylation factor-interacting protein 1 antibody; Arfaptin antibody; Arfaptin-1 antibody; ARFIP 1 antibody; Arfip1 antibody; ARFP1_HUMAN antibody; HSU52521 antibody; MGC117369 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ARFIP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in controlling biogenesis of secretory granules at the trans-Golgi network. Mechanisitically, binds ARF-GTP at the neck of a growing secretory granule precursor and forms a protective scaffold. Once the granule precursor has been completely loaded, active PRKD1 phosphorylates ARFIP1 and releases it from ARFs. In turn, ARFs induce fission. Through this mechanism, ensures proper secretory granule formation at the Golgi of pancreatic beta cells.
Gene References into Functions
  1. inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in fibrosarcoma cells PMID: 12606037
Subcellular Location
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Tissue Specificity
Ubiquitously expressed. Higher levels in liver, pancreas, placenta, skeletal muscle and heart.
Database Links

HGNC: 21496

OMIM: 605928

KEGG: hsa:27236

STRING: 9606.ENSP00000296557

UniGene: Hs.416089

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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