ARHGAP12 Antibody

Code CSB-PA070306
Size US$100
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Product Details

Uniprot No.
Target Names
ARHGAP12
Alternative Names
Arhgap12 antibody; FLJ10971 antibody; FLJ20737 antibody; FLJ21785 antibody; RHG12_HUMAN antibody; Rho GTPase activating protein 12 antibody; Rho GTPase-activating protein 12 antibody; Rho type GTPase activating protein 12 antibody; Rho-type GTPase-activating protein 12 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human ARHGAP12.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Gene References into Functions
  1. molecular cloning and characterization of ARHGAP12 PMID: 11854031
  2. Met-driven invasive growth involves transcriptional regulation of Arhgap12. PMID: 18504429
  3. ARHGAP12 inactivates RAC1, thereby impairing cell motility, invasion and adhesion to the extracellular matrix. The gene is transcriptionally suppressed by Hepatocyte Growth Factor in vitro. PMID: 18504429
Database Links

HGNC: 16348

OMIM: 610577

KEGG: hsa:94134

STRING: 9606.ENSP00000345808

UniGene: Hs.499264

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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