ARHGEF10L Antibody

Code CSB-PA002042GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ARHGEF10L
Alternative Names
ARGAL_HUMAN antibody; ARHGEF10L antibody; GrinchGEF antibody; KIAA1626 antibody; Rho guanine nucleotide exchange factor 10-like protein antibody; RP11-473A10.1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human ARHGEF10L
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.
Gene References into Functions
  1. Inherited variants in ARHGEF10L and AKAP6, with potential transcriptional regulatory function and association with Epithelial ovarian cancer risk, warrant investigation in independent Epithelial ovarian cancer study populations. PMID: 29979793
  2. In intact cells, GrinchGEF induced specifically Rho activation and enhanced RhoA-C-specific downstream effects. PMID: 16112081
Subcellular Location
Cytoplasm.
Tissue Specificity
Detected in heart, liver, skeletal muscle, kidney and pancreas.
Database Links

HGNC: 25540

OMIM: 612494

KEGG: hsa:55160

STRING: 9606.ENSP00000355060

UniGene: Hs.443460

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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