ARL8A Antibody

Code CSB-PA002099GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ARL8A
Alternative Names
ARL8A antibody; ARL10B antibody; GIE2ADP-ribosylation factor-like protein 8A antibody; ADP-ribosylation factor-like protein 10B antibody; Novel small G protein indispensable for equal chromosome segregation 2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ARL8A
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in lysosome motility. In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. May play a role in chromosome segregation.
Gene References into Functions
  1. Overexpression of Arl8a or Arl8b results in a microtubule-dependent redistribution of lysosomes towards the cell periphery. Live cell imaging suggested a role for Arl8a and Arl8b as positive regulators of lysosomal transport.[Ar18a] [Ar18b] PMID: 16537643
Subcellular Location
Late endosome membrane. Lysosome membrane. Cytoplasm, cytoskeleton, spindle. Cell projection, axon. Cell junction, synapse.
Protein Families
Small GTPase superfamily, Arf family
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 25192

OMIM: 616597

KEGG: hsa:127829

STRING: 9606.ENSP00000272217

UniGene: Hs.497399

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