ARMC8 Antibody

1. Knockdown of ARMC8 significantly inhibited osteosarcoma cell proliferation in vitro and markedly inhibited xenograft tumor growth in vivo. ARMC8 silencing also suppressed the epithelial-mesenchymal transition (EMT) phenotype, as well as inhibited the migration and invasion of osteosarcoma cells. PMID: 27712595
2. results indicate that Armc8 may be a potential cancer marker in hepatocellular carcinoma PMID: 26944057
3. invasiveness and migration capacity of HT29 cells transfected with ARMc8 were significantly greater than those of control cells (p < 0.001), while ARMc8 siRNA treatment significantly reduced cell invasion and migration in LoVo cells PMID: 26081621
4. ARMc8 may enhance the invasion and metastasis of ovarian cancer cells PMID: 26232863
5. Armc8 expression was elevated during atypia-to-carcinoma progression and associated with cancer development of breast carcinoma. PMID: 25119601
6. Data suggest that armadillo repeat containing protein 8 (ARMC8) might serve as a therapeutic target in non-small cell lung cancer (NSCLC). PMID: 24894675

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HGNC: 24999

KEGG: hsa:25852

STRING: 9606.ENSP00000420333

UniGene: Hs.744868