ASB9 Antibody

1. Model of ASB9 in complex with its substrate, creatine kinase, reveals a mechanism for dynamic ubiquitin transfer. PMID: 27396830
2. Molecular docking yielded a structural model consistent with all of the data that suggested the N-terminal residues of ASB9(1-252) may lie in one CK active site. This model was corroborated by enzymatic activity assays and mutational analysis. PMID: 25654263
3. ASB9 is unstable alone but forms a stable ternary complex with EloBC that binds with high affinity to the Cullin 5 N-terminal domain. PMID: 23837592
4. His103 and Phe107 in hASB9-2 are essential for binding to CKB. PMID: 22418839
5. The results of the present study suggest that ASB9 is a useful prognostic marker for colorectal cancer PMID: 20878058
6. ASB9 interacts with the creatine kinase system and negatively regulates cell growth. PMID: 20302626
7. The splice variant of hASB9, hASB9-2 protein, was cloned, overexpressed, and crystallized and the data showed that the cubic hASB9-2 crystal belongs to space group P4(3)32 with unit-cell parameters. PMID: 18680464
8. The purified ASB9-2 protein, the splice variant of ASB9 with only one ankyrin repeat domain, was crystallized and diffracted to 2.2A resolution. PMID: 19275750

Show More

Hide All

HGNC: 17184

OMIM: 300890

KEGG: hsa:140462

STRING: 9606.ENSP00000369855

UniGene: Hs.19404