Adh7 Antibody

Datasheet

Code	CSB-PA717544LA01MO
Size	US$166
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Image	Western Blot Positive WB detected in: Mouse liver tissue All lanes: Adh7 antibody at 3.5µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) Adh7 Polyclonal antibody

Uniprot No.

Q64437

Target Names

Adh7

Alternative Names

Adh7 antibody; Adh-3 antibody; Adh3All-trans-retinol dehydrogenase [NAD(+)] ADH7 antibody; EC 1.1.1.105 antibody; ADH-C2 antibody; Alcohol dehydrogenase 7 antibody; Alcohol dehydrogenase class 4 mu/sigma chain antibody; EC 1.1.1.1 antibody; Alcohol dehydrogenase class IV mu/sigma chain antibody; Gastric alcohol dehydrogenase antibody; Omega-hydroxydecanoate dehydrogenase ADH7 antibody; EC 1.1.1.66 antibody; Retinol dehydrogenase antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse Alcohol dehydrogenase class 4 mu/sigma chain protein (1-374AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

The Adh7 Antibody (Product code: CSB-PA717544LA01MO) is Non-conjugated. For Adh7 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA717544LB01MO	Adh7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA717544LC01MO	Adh7 Antibody, FITC conjugated
Biotin	CSB-PA717544LD01MO	Adh7 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, aldehyde and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation.

Gene References into Functions

ADH3 promotes liver fibrosis by enhancing hepatic stellate cell activation and inhibiting natural killer cell activity PMID: 24668648
Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3 PMID: 11959987
ADH1 functions as the primary enzyme responsible for efficient oxidative clearance of excess retinol, thus providing protection and increased survival during vitamin A toxicity, ADH3 plays a secondary role PMID: 12027900
Cellular expression of Adh3 in the GUI tract was studied. PMID: 17257171

Subcellular Location

Cytoplasm.

Protein Families

Zinc-containing alcohol dehydrogenase family, Class-IV subfamily

Tissue Specificity

High expression in the stomach mucosa. Lower expression in eye, thymus, skin and ovary. Very low expression in small intestine, liver and uterus.

Database Links

KEGG: mmu:11529

STRING: 10090.ENSMUSP00000087633

UniGene: Mm.8473

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Phage Display Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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