BANP Antibody

1. Cdc20 functions as an important negative regulator of SMAR1 in higher grades of cancer PMID: 28617439
2. Dysregulated circ-BANP appears to have an important role in colorectal cancer cells. PMID: 28103507
3. results reveal the complex molecular mechanism underlying SMAR1-mediated signal-dependent and -independent regulation of alternative splicing via Sam68 deacetylation PMID: 26080397
4. SMAR1-mediated regulation of repair and apoptosis via a complex crosstalk involving Ku70, HDAC6 and Bax. PMID: 25299772
5. Data indicate the role of SMAR1 protein in NF-kappaappa B dependent transcriptional regulation of pro-angiogenic chemokine interleukin-8 (IL-8). PMID: 25239884
6. indicate a crucial role for SMAR1 in restraining breast cancer cell migration and suggest the candidature of this scaffold matrix-associated region-binding protein as a tumor suppressor. PMID: 25086032
7. SMAR1 has a role in repressing c-Fos-mediated HPV18 E6 transcription through alteration of chromatin histone deacetylation PMID: 25157104
8. During hemin-induced erythroid differentiation, enhanced expression of SMAR1 negatively correlates with miR-320a expression. PMID: 23876508
9. TCF-4, beta-catenin, and SMAR1 tether at the -143-nucleotide site on the HIV LTR to inhibit HIV promoter activity. PMID: 22674979
10. Results indicate that SMAR1 is an important player in p300-p53 regulated DNA damage signalling pathway and can exert its effect on apoptosis in a transcription independent manner. PMID: 22074660
11. multiple roles of nuclear matrix associated protein SMAR1 in regulating various cellular target genes involved in cell growth, apoptosis and tumorigenesis.(REVIEW) PMID: 20709157
12. A novel mechanism of regulation of oxidative stress by ATM through modulation of SMAR1-AKR1a4 complex, is proposed. PMID: 20097305
13. SMAR1 plays a central role in coordinating p53 and TGFbeta pathways in human breast cancer. PMID: 17668048
14. report Prostaglandin A2 (PGA2) induced binding of HSP70 to a novel site on phi1 SMAR1 5' UTR which stabilizes the wild type transcript and leads to subsequent increase in SMAR1 protein levels. PMID: 20153327
15. On mild DNA damage, SMAR1 selectively represses BAX and PUMA through binding to the MAR independently of inducing p53 deacetylation through HDAC1. PMID: 20075864
16. Human breast cancer tissue sections that showed reduced SMAR1 expression exhibited increased surface roughness. PMID: 19799771
17. SMAR1 plays an important role in the regulation of T cell development as well as V(D)J recombination PMID: 15623522
18. SMAR1 regulates cyclin D1 by modification of chromatin through the SIN3/histone deacetylase 1 complex PMID: 16166625
19. tumor suppressor SMAR1 downregulates Cytokeratin 8 gene expression by modulating p53-mediated transactivation of this gene PMID: 18822384
20. tumor suppressor protein SMAR1 can modulate NF-kappaB transactivation and inhibit tumorigenesis by regulating NF-kappaB target genes PMID: 18981184
21. Results highlight the role of SMAR1 in masking the active phosphorylation site of p53, enabling the deacetylation of p53 by HDAC1-MDM2 complex, thereby regulating the p53 transcriptional response during stress rescue. PMID: 19303885
22. Identification of a novel mouse MAR-binding protein, named SMAR1, which shares homology with SATB1 and Cux in the MAR-binding domain/Cut repeat and also with the tetramerization domain of a B cell-specific MAR-binding protein, Bright. PMID: 10950932

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HGNC: 13450

OMIM: 611564

KEGG: hsa:54971

STRING: 9606.ENSP00000286122

UniGene: Hs.461705