BEST3 Antibody

Code CSB-PA002668GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
BEST3
Alternative Names
BEST3; VMD2L3; Bestrophin-3; Vitelliform macular dystrophy 2-like protein 3
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human BEST3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Gene References into Functions
  1. results demonstrated that Best-3 is an endogenous inhibitor of NF-kappaB signaling pathway in endothelial cells, suggesting that forced Best-3 expression may be a novel approach for the treatment of vascular inflammatory diseases. PMID: 25329324
  2. These results suggest that an auto-inhibitory mechanism in C termini of bestrophin 3 may be universal among bestrophins investigated in the study. PMID: 17442670
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Bestrophin family
Tissue Specificity
Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.
Database Links

HGNC: 17105

OMIM: 607337

KEGG: hsa:144453

STRING: 9606.ENSP00000332413

UniGene: Hs.280782

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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