BLID Antibody

Code CSB-PA818276ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA818276ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BLID Polyclonal antibody
Uniprot No.
Target Names
BLID
Alternative Names
BH3-like motif containing; cell death inducer antibody; BH3-like motif-containing cell death inducer antibody; BLID antibody; BLID_HUMAN antibody; BRCC2 antibody; breast cancer cell 2 antibody; Breast cancer cell protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human BH3-like motif-containing cell death inducer protein (1-108AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Functions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death.
Gene References into Functions
  1. Results showed that the expression of BLID is frequently downregulated in non-small cell lung tumors and cell lines and inversely correlates with miR-575 expression. PMID: 25728273
  2. loss of BLID may contribute to the progression of intraductal proliferation lesions to breast cancer. PMID: 24532431
  3. BRCC2 functions as a novel tumor suppressor in breast cancer and may be a potential therapeutic target for breast cancer management. PMID: 23928696
  4. Frequent loss of the BLID gene is observed in early-onset breast cancer. PMID: 21846966
  5. Tag single nucleotide polymorphisms near the BLID and LOC399959 genes are not susceptibility loci for high myopia in the Chinese Han population. PMID: 21031016
  6. BLID upregulation resulting from a novel IGH translocation is associated with childhood B-Cell precursor acute lymphoblastic leukemia. PMID: 20544842
  7. BLID is a new binding partner of Bcl-X(L) and a significant prognostic factor in breast cancer PMID: 20400521
  8. BRCC2 is a novel BH3-like domain-containing protein which induces apoptosis in a caspase-dependent manner PMID: 15069058
  9. BLID gene is assigned to 11p24.1. PMID: 18940476
  10. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19779542

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Subcellular Location
Cytoplasm. Mitochondrion. Note=Lower abundance in mitochondrion than in cytoplasm.
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 33495

OMIM: 608853

KEGG: hsa:414899

STRING: 9606.ENSP00000453153

UniGene: Hs.686109

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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