BTBD1 Antibody

Code CSB-PA002840GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
BTBD1
Alternative Names
BTBD1 antibody; C15orf1 antibody; NS5ATP8BTB/POZ domain-containing protein 1 antibody; Hepatitis C virus NS5A-transactivated protein 8 antibody; HCV NS5A-transactivated protein 8 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human BTBD1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis.
Gene References into Functions
  1. Interaction of BTBD1 and BTBD2 with TOP1 requires TOP1 residues 236 and 237, the same residues required to enhance the infectivity of progeny virions when TOP1 is expressed in African Green Monkey producer cells. PMID: 21092135
  2. subcellular colocalization of BTBD1 and BTBD2 to cytoplasmic bodies; TRIM5delta colocalized with BTBD1/2 and appeared to serve as a scaffold for the assembly of endogenous BTBD1/2 proteins PMID: 12878161
  3. BTBD1 is essential for myogenic differentiation PMID: 15486563
Subcellular Location
Cytoplasm.
Tissue Specificity
Ubiquitous; highest levels in testes, heart and skeletal muscle.
Database Links

HGNC: 1120

OMIM: 608530

KEGG: hsa:53339

STRING: 9606.ENSP00000261721

UniGene: Hs.459149

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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