B cell translocation gene 4 antibody; BTG family member 4 antibody; Btg4 antibody; BTG4_HUMAN antibody; MGC33003 antibody; PC3B antibody; Protein BTG4 antibody; Protein PC3b antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human BTG4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E. Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development.
Gene References into Functions
BTG4 could contribute to chronic lymphocytic leykemia pathogenesis following inactivation by haploinsufficiency. PMID: 15672409
miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC PMID: 18519671
these data support BTG4 as a candidate tumor suppressor gene that is epigenetically silenced in the majority of gastric cancers. PMID: 19576178
Protein Families
BTG family
Tissue Specificity
Expressed in oocytes after germinal vesicle breakdown. Expressed in testis and in olfactory epithelium.