CDKL2 Antibody

Code CSB-PA294019
Size US$297
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  • Western blot analysis of extracts from 293 cells and Jurkat cells, using CDKL2 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDKL2 Polyclonal antibody
Uniprot No.
Target Names
CDKL2
Alternative Names
CDKL2Cyclin-dependent kinase-like 2 antibody; EC 2.7.11.22 antibody; Protein kinase p56 KKIAMRE antibody; Serine/threonine-protein kinase KKIAMRE antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human CDKL2.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Results showed that the methylation levels of CDKL2 were higher in hepatocellular carcinoma (HCC) cell lines and tissues but the mRNA expression levels decreased both in HCC tissues and cell lines. CDKL2 status seems to correlate with tumor size and may play an important role in hepatocarcinogenesis. PMID: 30292871
  2. High CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression. PMID: 25333262
  3. We hypothesized that LA might induce dissociation of p56(Lck) from CD4, thus leading to its downmodulation. PMID: 16631599
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Tissue Specificity
Expressed in testis and kidney, and at lower level in brain and lung.
Database Links

HGNC: 1782

OMIM: 603442

KEGG: hsa:8999

STRING: 9606.ENSP00000412365

UniGene: Hs.591698

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