CIDEB Antibody

Code CSB-PA12869A0Rb
Size US$166
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  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA12869A0Rb at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA12869A0Rb at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CIDEB Polyclonal antibody
Uniprot No.
Target Names
CIDEB
Alternative Names
Cell death activator CIDE B antibody; Cell death activator CIDE-B antibody; Cell death inducing DFFA like effector B antibody; Cell death-inducing DFFA-like effector B antibody; CIDEB antibody; CIDEB_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cell death activator CIDE-B protein (80-145AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CIDEB Antibody (Product code: CSB-PA12869A0Rb) is Non-conjugated. For CIDEB Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA12869B0Rb CIDEB Antibody, HRP conjugated ELISA
FITC CSB-PA12869C0Rb CIDEB Antibody, FITC conjugated
Biotin CSB-PA12869D0Rb CIDEB Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Activates apoptosis.; (Microbial infection) Involved in Hepatatis C virus (HCV) assembly and required for HCV entry into hepatocytes.
Gene References into Functions
  1. High Cideb expression is associated with Ulcerative Colitis. PMID: 28719542
  2. CIDEB interacts with the HCV NS5A protein, and the N terminus of CIDEB and the domain I of NS5A are involved in this interaction. PMID: 27282740
  3. these data revealed that Cideb plays an important role in controlling intestinal chylomicron lipidation. PMID: 24831470
  4. this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of CIDEB PMID: 27213693
  5. CIDEB downregulation may contribute to HCV-induced hepatic steatosis PMID: 26865724
  6. CIDEB can act as an anti-HCV host factor and contribute to altered triglyceride homeostasis. PMID: 24980280
  7. Authors found CIDEB to be an essential cofactor for hepatitis C virus entry into hepatocytes. PMID: 24829338
  8. this work highlights CIDEB's role in lipid droplet (LD) fusion, and presents a new model system to study the PGC-1alpha/CIDEB pathway's role in LD dynamics and the VLDL pathway. PMID: 24161736
  9. CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma. PMID: 23475172
  10. A novel mechanism for the cell-specific transcription of the human CIDE-B gene, which involves epigenetic and genetic control at separate respective promoters is reported. PMID: 16248853

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Tissue Specificity
Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen.
Database Links

HGNC: 1977

OMIM: 604441

KEGG: hsa:27141

STRING: 9606.ENSP00000258807

UniGene: Hs.642693

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