CRNN Antibody

1. This study showed a significant correlation between LOH/MSI at 1q21.3 with clinical outcomes and that downregulation of CRNN gene could be considered as a prognostic marker of OSCC. PMID: 25846277
2. The single-nucleotide polymorphisms of CRNN (rs941934) and RPTN (rs3001978, rs28441202) may contribute to Atopic Dermatitis development, but further studies on a larger group of Atopic Dermatitis patients are needed to verify this assumption. PMID: 28219068
3. Loss of CRNN expression correlated with advanced tumor length, greater tumor invasion depth, lymph node metastasis, and poor survival in patients with esophageal squamous cell carcinoma. PMID: 24263008
4. Findings demonstrate that CRNN is a tumor suppressor gene that plays a critical tumor suppressive role in ESCC. PMID: 23894350
5. cornulin is an important molecule in normal esophageal pathology and is likely lost during the conversion of normal to neoplastic epithelium PMID: 22560086
6. SEP53 may be a component of the mucosal/epithelial innate immune response engaged in an ongoing interaction with a pathogen PMID: 17925851
7. Results describe the cloning of porcine SEP53, its homology to the human protein, and its expression in the esophagus and in gastric squamous epithelium. PMID: 18465210
8. CRNN mRNA expression is decreased in eczematous skin PMID: 19133922

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HGNC: 1230

OMIM: 611312

KEGG: hsa:49860

STRING: 9606.ENSP00000271835

UniGene: Hs.242057