CYP2C18/CYP2C8/CYP2C9/CYP2C19 Antibody

Code CSB-PA834244
Size US$297
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  • Western blot analysis of extracts from LOVO cells, using Cytochrome P450 2C8/9/18/19 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CYP2C18/CYP2C8/CYP2C9/CYP2C19 Polyclonal antibody
Uniprot No.
Target Names
CYP2C18/CYP2C8/CYP2C9/CYP2C19
Alternative Names
CYP2C18Cytochrome P450 2C18 antibody; EC 1.14.14.1 antibody; CYPIIC18 antibody; Cytochrome P450-6b/29c antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human Cytochrome P450 2C8/9/18/19.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
A cytochrome P450 monooxygenase involved in retinoid metabolism. Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may modulate atRA signaling and clearance. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein Families
Cytochrome P450 family
Database Links

HGNC: 2620

OMIM: 601131

KEGG: hsa:1562

STRING: 9606.ENSP00000285979

UniGene: Hs.511872

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