CYP4X1 Antibody

Code CSB-PA847606LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA847606LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA847606LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CYP4X1 Polyclonal antibody
Uniprot No.
Target Names
CYP4X1
Alternative Names
CYP4X1; UNQ1929/PRO4404; Cytochrome P450 4X1; CYPIVX1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cytochrome P450 4X1 protein (35-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CYP4X1 Antibody (Product code: CSB-PA847606LA01HU) is Non-conjugated. For CYP4X1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA847606LB01HU CYP4X1 Antibody, HRP conjugated ELISA
FITC CSB-PA847606LC01HU CYP4X1 Antibody, FITC conjugated
Biotin CSB-PA847606LD01HU CYP4X1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling. Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Gene References into Functions
  1. Key residues were identified to be responsible for the binding of arachidonic acid and anandamide with orphan human cytochrome P450 4X1. PMID: 25595103
  2. PPARalpha has a role in CYP4X1 regulation, and the glucocorticoid and progesterone receptors have roles in CYP4Z1 gene activation PMID: 15797250
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein Families
Cytochrome P450 family
Tissue Specificity
Expressed in brain, heart, kidney and skin and, at lower levels, in skeletal muscle and liver. In the brain, high levels are detected in amygdala and lower levels in globus pallidus and cerebellum. In the heart, very high levels in aorta, but very low lev
Database Links

HGNC: 20244

OMIM: 614999

KEGG: hsa:260293

STRING: 9606.ENSP00000360968

UniGene: Hs.439760

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