Ccl9 Antibody

Code CSB-PA09119A0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Ccl9 Polyclonal antibody
Uniprot No.
Target Names
Ccl9
Alternative Names
CCF18 antibody; Ccl9 antibody; CCL9(31-101) antibody; CCL9_MOUSE antibody; Chemokine CC motif ligand 9 antibody; Macrophage inflammatory protein 1-gamma antibody; Macrophage inflammatory protein-related protein 2 antibody; MIP-1-gamma antibody; MRP-2 antibody; SCYA10 antibody; SCYA9 antibody; Small inducible cytokine A9 antibody; Small-inducible cytokine A9 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse C-C motif chemokine 9 protein (22-114AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated

The Ccl9 Antibody (Product code: CSB-PA09119A0Rb) is Non-conjugated. For Ccl9 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA09119B0Rb Ccl9 Antibody, HRP conjugated ELISA
FITC CSB-PA09119C0Rb Ccl9 Antibody, FITC conjugated
Biotin CSB-PA09119D0Rb Ccl9 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.
Gene References into Functions
  1. CCL9 secreted by splenic macrophages induces a CCR1dependent accumulation of MDSCs. PMID: 30365155
  2. Results show that MIP-1g promotes tumor cell growth in vitro through the activation of NFkB pathway in colorectal tumor cells. PMID: 28108624
  3. we report that chemokine CCL9 was highly induced in Gr-1(+)CD11b(+) immature myeloid cells and in premetastatic lung in tumor-bearing mice PMID: 26483204
  4. Plasmid codelivery of murine CCL19 and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues. PMID: 23858028
  5. There is protein-DNA interaction between ETV5 and Ccl9, suggesting that ETV5 might be a direct regulator of Ccl9 expression. PMID: 20799334
  6. Results reveal the potential involvement of CCL9 and CCR1 in macrophage and microglial cells by CpG-ODNs and may help understanding the role of the chemokine/chemokine receptor pairs in macrophage/microglia under physiologic and pathologic conditions. PMID: 19883904
  7. MRP-2 may be an important contributing factor in the development of atherosclerosis PMID: 12173416
  8. CCL9 and its receptor CCR1 are the major chemokine and receptor species expressed by osteoclasts, CCL9 has a role in the regulation of bone resorption PMID: 12397598
  9. An important role for CCL9 is demonstrated in the recruitment of CD11b+ dendritic cells to the dome regions of mouse Peyer's patches. PMID: 12960300
  10. MIP-1 gamma plays an important role in the differentiation & survival of osteoclasts, & bone resorption, most likely via an autocrine pathway. PMID: 15265944
  11. Keratinocyte-derived chemokine (KC) and MIP-2 alpha differ in their mediation of neutrophil function (apoptosis and chemotaxis) and contribution to the pathogenesis of lung injury following hemorrhage subsequent to sepsis. PMID: 15961314
  12. BCR/ABL repressed CCL9 expression at the transcriptional level PMID: 17160016
  13. involved in calcium mobilization and chemotaxis PMID: 11500837

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Subcellular Location
Secreted.
Protein Families
Intercrine beta (chemokine CC) family
Tissue Specificity
Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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