DCAF8 Antibody

Datasheet

Code	CSB-PA725896HA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Mouse heart tissue, Mouse lung tissue All lanes: DCAF8 antibody at 3.5μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 67, 31 kDa Observed band size: 67 kDa Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA725896HA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA725896HA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DCAF8 Polyclonal antibody

Uniprot No.

Q5TAQ9

Target Names

DCAF8

Alternative Names

DCAF8 antibody; H326 antibody; WDR42ADDB1- and CUL4-associated factor 8 antibody; WD repeat-containing protein 42A antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human DDB1- and CUL4-associated factor 8 protein (1-135AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DCAF8 Antibody (Product code: CSB-PA725896HA01HU) is Non-conjugated. For DCAF8 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA725896HB01HU	DCAF8 Antibody, HRP conjugated	ELISA
FITC	CSB-PA725896HC01HU	DCAF8 Antibody, FITC conjugated
Biotin	CSB-PA725896HD01HU	DCAF8 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:2000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Gene References into Functions

DCAF8 p.R317C mutation is responsible for specific variety of HMSN2 with infrequent giant axons and mild cardiomyopathy. PMID: 24500646
WDR42A is a nucleocytoplasmic shuttling protein. PMID: 22500989
while RNF10 and WDR42A or VP22 alone showed distinct subcellular localization patterns, RNF10 and WDR42A were relocated when co-expressed with VP22 or its homologues; these potential host cell factors of VP22 might expand the list of host targets of VP22 PMID: 21424732

Involvement in disease

Giant axonal neuropathy 2, autosomal dominant (GAN2)

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

WD repeat DCAF8 family

Database Links

HGNC: 24891

OMIM: 610100

KEGG: hsa:50717

STRING: 9606.ENSP00000451235

UniGene: Hs.632447

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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