DDIT4L Antibody

Code CSB-PA049554
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA049554(DDIT4L Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
DDIT4L
Alternative Names
DDIT4L antibody; REDD2 antibody; RTP801LDNA damage-inducible transcript 4-like protein antibody; HIF-1 responsive protein RTP801-like antibody; Protein regulated in development and DNA damage response 2 antibody; REDD-2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human DDIT4L
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Gene References into Functions
  1. mediates monocyte cell death through a reduction in thioredoxin-1 expression PMID: 19268525
  2. Promoter methylation and differential gene expression of five markers: COL1A2, NPM2, HSPB6, DDIT4L and MT1G were validated by sequencing of bisulfite-modified DNA and real-time reverse transcriptase PCR, respectively. PMID: 19491193
Subcellular Location
Cytoplasm.
Protein Families
DDIT4 family
Tissue Specificity
Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Database Links

HGNC: 30555

OMIM: 607730

KEGG: hsa:115265

STRING: 9606.ENSP00000354830

UniGene: Hs.480378

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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