Recombinant Human DNA damage-inducible transcript 4-like protein (DDIT4L)

Code CSB-YP853399HU
MSDS
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Source Yeast
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Code CSB-EP853399HU
MSDS
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Source E.coli
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Code CSB-EP853399HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP853399HU
MSDS
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Source Baculovirus
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Code CSB-MP853399HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
DDIT4L
Uniprot No.
Alternative Names
DDIT4L; REDD2; RTP801LDNA damage-inducible transcript 4-like protein; HIF-1 responsive protein RTP801-like; Protein regulated in development and DNA damage response 2; REDD-2
Species
Homo sapiens (Human)
Expression Region
1-193
Target Protein Sequence
MVATGSLSSK NPASISELLD CGYHPESLLS DFDYWDYVVP EPNLNEVIFE ESTCQNLVKM LENCLSKSKQ TKLGCSKVLV PEKLTQRIAQ DVLRLSSTEP CGLRGCVMHV NLEIENVCKK LDRIVCDSSV VPTFELTLVF KQENCSWTSF RDFFFSRGRF SSGFRRTLIL SSGFRLVKKK LYSLIGTTVI EGS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Gene References into Functions
  1. mediates monocyte cell death through a reduction in thioredoxin-1 expression PMID: 19268525
  2. Promoter methylation and differential gene expression of five markers: COL1A2, NPM2, HSPB6, DDIT4L and MT1G were validated by sequencing of bisulfite-modified DNA and real-time reverse transcriptase PCR, respectively. PMID: 19491193
Subcellular Location
Cytoplasm.
Protein Families
DDIT4 family
Tissue Specificity
Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Database Links

HGNC: 30555

OMIM: 607730

KEGG: hsa:115265

STRING: 9606.ENSP00000354830

UniGene: Hs.480378

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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