DDX25 Antibody

Datasheet

Code	CSB-PA006615GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9UHL0

Target Names

DDX25

Alternative Names

DDX25 antibody; GRTHATP-dependent RNA helicase DDX25 antibody; EC 3.6.4.13 antibody; DEAD box protein 25 antibody; Gonadotropin-regulated testicular RNA helicase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human DDX25

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development.

Gene References into Functions

Analysed the association of GRTH gene IVS6+55G/T and c.852C/T polymorphisms with male infertility. The c.852 T allele was associated with an increased risk of male infertility (OR: 3.16, P = 0.008), whereas IVS6+55G/T allele conferred no risk. PMID: 24168058
multifunctional RNA helicase that is an essential regulator of spermatogenesis PMID: 19875492
SNP IVS6+55G-->T and c.852C-->T of GRTH gene may be associated with male infertility with azoospermia or severe oligozoospermia. PMID: 16293649
Data show that the Arg(242)His missense mutation of the GRTH/DDX25 gene associated with expression of a protein with reduced basicity, and the absence of the phospho-GRTH species, could impact on germ cell development and/or function. PMID: 17848414
The association of GRTH mutations with male infertility underlines the importance of GRTH as a central, post-transcriptional regulator of spermatogenesis. PMID: 17889551

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

DEAD box helicase family

Tissue Specificity

Highly expressed in the Leydig and germ cells of the testis and weakly expressed in the pituitary and hypothalamus.

Database Links

HGNC: 18698

OMIM: 607663

KEGG: hsa:29118

STRING: 9606.ENSP00000263576

UniGene: Hs.420263

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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