DHX29 Antibody

1. A critical role for DHX29 in innate immune response; molecular insights into the mechanisms by which DHX29 recognizes 5' structured EMCV RNA and interacts with MDA5 for potent type I interferon signaling and antiviral immunity. PMID: 29462185
2. DHX29 and eIF3 cooperate in scanning on structured mRNAs. Our findings support previous genetic data on the role of eIF3 during scanning PMID: 27733651
3. DHX29 is another example of an initiation factor contributing to start codon selection. PMID: 27067542
4. Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system. PMID: 24821782
5. Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs. PMID: 23047696
6. Down-regulation of DHX29 leads to impaired translation, resulting in disassembly of polysomes and accumulation of mRNA-free 80S monomers. DHX29 depletion also impedes cancer cell growth in culture and in xenografts. PMID: 20018725
7. Study reports that these 7 eIFs are not sufficient for efficient 48S complex formation on mRNAs with highly structured 5'UTRs, and that this process requires the DExH-box protein DHX29. PMID: 19109895

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HGNC: 15815

OMIM: 612720

KEGG: hsa:54505

STRING: 9606.ENSP00000251636

UniGene: Hs.593268