DMKN Antibody

Datasheet

Code	CSB-PA006965LA01HU
Size	US$166
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Image	Western blot All lanes: DMKN antibody at 6µg/ml Lane 1: Mouse kidney tissue Lane 2: Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 48, 16, 37, 46, 39, 42, 36, 21, 19, 17, 15, 10, 47 kDa Observed band size: 42 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DMKN Polyclonal antibody

Uniprot No.

Q6E0U4

Target Names

DMKN

Alternative Names

Dermokine antibody; DMKN antibody; DMKN_HUMAN antibody; Epidermis-specific secreted protein SK30/SK89 antibody; FLJ79374 antibody; UNQ729 antibody; UNQ729/PRO1411 antibody; ZD52F10 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Dermokine protein (1-137AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DMKN Antibody (Product code: CSB-PA006965LA01HU) is Non-conjugated. For DMKN Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA006965LB01HU	DMKN Antibody, HRP conjugated	ELISA
FITC	CSB-PA006965LC01HU	DMKN Antibody, FITC conjugated
Biotin	CSB-PA006965LD01HU	DMKN Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May act as a soluble regulator of keratinocyte differentiation.

Gene References into Functions

we showed that DMKN loss of function in Patu-8988 and PANC-1 pancreatic cancer cell lines resulted in reduced phosphorylation of STAT3.these data suggested that DMKN could be a potential prognostic biomarker and therapeutic target in pancreatic cancer. PMID: 28795470
These results suggest that dermokine-beta delays early cutaneous wound healing in part by inhibiting expression of CXC chemokines containing the ERL-sequence motif. PMID: 23428944
Serum DK is a potential biomarker in intraductal papillary mucinous neoplasm and invasive ductal carcinoma, when used in combination with conventional biomarkers. PMID: 23060565
Dermokine-beta impairs ERK signaling through direct binding to GRP78 PMID: 22735594
Dmkndelta activates Rab5 function and thus is involved in the early endosomal trafficking. PMID: 21423773
Analysis of alternative spliced transcripts produced from the dermokine gene. PMID: 16374476
Dermokine gene is expressed in epithelial tissues other than the skin and this expression is transcriptionally and posttranscriptionally complex. PMID: 17380110

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Subcellular Location

Secreted.

Protein Families

Dermokine family

Tissue Specificity

Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expr

Database Links

HGNC: 25063

KEGG: hsa:93099

STRING: 9606.ENSP00000342012

UniGene: Hs.417795

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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