DNAJC27 Antibody

Code CSB-PA007032GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
DNAJC27
Alternative Names
DJC27_HUMAN antibody; DKFZp434N211 antibody; DnaJ (Hsp40) homolog, subfamily C, member 27 antibody; DnaJ homolog subfamily C member 27 antibody; DNAJC27 antibody; rab and DnaJ domain containing antibody; Rab and DnaJ domain-containing protein antibody; RABJS antibody; Ras associated protein Rap1 antibody; RBJ antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human DNAJC27
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
Gene References into Functions
  1. these data suggest that RBJ may be an oncogenic Ras-related small GTPase mediating nuclear accumulation of active MEK1/MEK2 in tumor progression. PMID: 24746703
Subcellular Location
Nucleus.
Protein Families
Small GTPase superfamily, Rab family
Tissue Specificity
Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers.
Database Links

HGNC: 30290

OMIM: 613527

KEGG: hsa:51277

STRING: 9606.ENSP00000264711

UniGene: Hs.434993

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