DNM3 Antibody

Datasheet

Code	CSB-PA599880
Size	US$166
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Image	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: CSB-PA599880(DNM3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q9UQ16

Target Names

DNM3

Alternative Names

testicular dynamin antibody; testicular antibody; DNM 3 antibody; DNM3 antibody; DNM3 protein antibody; Dyn3 antibody; DYN3_HUMAN antibody; Dyna III antibody; DynaIII antibody; dynamin 2 antibody; Dynamin antibody; Dynamin family member antibody; Dynamin testicular antibody; Dynamin-3 antibody; Dynamin3 antibody; EC 3.6.5.5 antibody; KIAA0820 antibody; MGC70433 antibody; T dynamin antibody; T-dynamin antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein of Human DNM3

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.

Gene References into Functions

In glioma, elevated miR-221 expression is a biomarker for glioma. DNM3 is a target of miR-221 and RELA regulates miR-221 expression. PMID: 27837435
Genetic variability in DNM3 modifies age of onset for LRRK2 Gly2019Ser parkinsonism. PMID: 27692902
DNM3 may be involved in risk of obsessive-compulsive disorder. PMID: 27023174
Microdeletion of DNM3 harboring miR199 and miR214 is associated with skeletal abnormalities. PMID: 26333682
DNM3 attenuates the proliferation and induces apoptosis of gastric cancer cells. PMID: 26784388
Data show that the classical dynamin DNM1 and DNM3 genes reach their maximum expression levels (100% of maximal expression) in all normal central nervous system tissues studied. PMID: 24673776
Data indicate that dynamin 3 (DNM3) harbors MEIS1 binding sites and is associated with differences in mean platelet volume (MPV). PMID: 22972982
DNM3 not only participates in megakaryocyte progenitor amplification, but is also involved in cytoplasmic enlargement and the formation of the demarcation membrane system. PMID: 21671749
Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients. PMID: 20700106
dynamin-3 and the postsynaptic adaptor Homer positions the endocytic zones near the postsynaptic density PMID: 17880892
Upon comparison of PBMC and skin samples of Sezary syndrome versus mycosis fungoides, CDO1 and DNM3 were found upregulated only in Sezary syndrome. PMID: 18033314
Dynamin 3 participates in the growth and development of megakaryocytes. PMID: 19007685

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Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton.

Protein Families

TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family

Database Links

HGNC: 29125

OMIM: 611445

KEGG: hsa:26052

STRING: 9606.ENSP00000350876

UniGene: Hs.654775

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Oxidative Phosphorylation Phospholipase D signaling pathway Endocytosis Synaptic vesicle cycle

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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